This report was performed to evaluate the gestational trophoblastic disease who were treated at Kangnam Sacred Heart Hospital from Jan. 1, 1986 to Dec. 31, 1994.
A retrospective review of hospital chart, we were studied 63 cases with gestational trophoblastic disease by the clinical characteristics and the outcome of management.
@ES The results were as follows:
@EN 1. Incidence of the gestational trophblastic disease compared with deliery was one per 209 deliveries.
2. The most frequent age & parity was 20 to 29 years old (66.7%) & 0 to 1 times(73%).
3. The clinical mamifestations were vaginal bleeding(79.4%), excessive uterine enlargement(30.2%), hyperemesis(28.6%), abdominal pain(27.0%) and etc.
4. The antecedent pregnancy preceding the diagnosis of a malignant gestational trophoblastic disease were abortion(37.5%), term pregnancy(25.0%), no pregnancy(37.%).
5. We divided the patient by the Hammond classification system : nonmetastasis(53 cases), metastasis(10 cases).
6. We divided the patient by the Bagshawe WHO prognostic scording system : low risk(21 cases), middle risk(27 cases) high risk(15 cases).
7. We divided the patient by the FIGO staging system : stage I(50 cases), stage II(2 cases), stage III(10 cases), stage IV( 1 cases).
8. The treatment regimens were consisted of D & E only(27%), D & E with chemotherapy(55.6%), and total abdominal hysterectomy with chemotherapy(14.3%),
9. The side effects after chemotherapy were hepatotoxicity(39.1%), gastrointestinal problem(37%), leukopenia(15.2%) and etc.
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